Akshay Pujari

Career Journey

Industry Experience

Rubedo Life Sciences

Rubedo Life Sciences

2020 – Present

Data Scientist II / Software Engineer II

  • Core member developing ALEMBIC, an AI-driven discovery and analysis platform integrating advanced computational algorithms with biology and chemistry.
Phaedon Institute

Phaedon Institute

2022 – Present

Web Infrastructure & Technology Lead (Ad hoc Volunteer)

  • The Phaedon Institute is a non-for-profit scientific think tank committed to pioneering advancements in the fields of aging and longevity sciences.
  • Independently led the end-to-end development of the organization’s website in close collaboration with founding board members; continue to actively oversee its web and technical operations on ad hoc basis. (www.phaedon.institute)
  • Contributed to the organization of Seno-Therapeutics Summit 2023 at the Buck Institute for Research on Aging; and 2025 Summit in Rome, Italy.
DiCE Therapeutics (Now Subsidiary of Eli Lilly and Company)

DiCE Therapeutics (Now Subsidiary of Eli Lilly and Company)

2017 – 2019

Research Associate II

  • Part of early-staged drug discovery company focused on discovering drug-like molecules for pharmaceutical targets based on innovative DNA-programmed combinatorial chemistry synthesis platform.
  • Designed and developed instrumentation, equipment, and procedures for novel fluidic pumps used for state of the art drug discovery using DNA-programmed combinatorial chemistry.
  • Assisted bioinformatics team in data analysis, interpretation and visualizations; presented data to the team on a regular basis.
  • Identified, tested, and experimented process and material improvements. Successfully improved the affinity chromatography binding efficiency by 1.5x, leading to updates in chemistry protocols.
  • Conducted literature and patent reviews to stay current with technologies and implemented them.
  • Managed lab equipment procurement, maintenance, and safety, including overseeing the disposal of hazardous chemicals.

Research & Academic Experience

University of Massachusetts Amherst

University of Massachusetts Amherst

2014 – 2017

Graduate Research Assistant

  • Investigated lymphatic fluid flow and valve dynamics in wild-type and genetically modified mice using in-vivo imaging and computational analyses.
  • Developed image analysis pipelines for particle tracking, edge detection, and vessel segmentation (Python, MATLAB, ImageJ, Imaris).
  • Conducted IHC experiments on mice tissues to identify differential protein expression of vascular endothelial cells subjected to varying flow regimes.
  • Studied hemodynamics in cardiovascular and cerebral vessels; explored implications for disease progression, including cancer metastasis.
  • Analyzed the vascular impact of stents, catheters, pharmacological agents and medical devices.
  • Conducted literature reviews on pathophysiology, development and treatment of vascular diseases such as atherosclerosis, thrombosis, aneurysms, myocardial infarction and lymphedema.
  • Presented findings at multiple symposia; contributed to manuscripts and scientific figures as lead author on publications.
  • Mentored junior lab members and presented journal articles in lab meetings.
Kolhapur Institute of Technology

Kolhapur Institute of Technology

2009 – 2013

Bachelor of Engineering – Mechanical Engineering

  • Graduated with honors.
  • Awarded Best Project at ISTE National Convention.
  • Held leadership roles in student council and athletics.
    • Elected by a student body of 3,000+ to the College Student Council.
    • Oversaw intercollegiate participation in state and national-level sports tournaments.
    • Served as Captain of the Chess Team, representing the college at national tournaments.
    • Led logistics, scheduling, and team selection across multiple disciplines.
    • Collaborated with college leadership on event planning and coordination.